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Cancer and a plant based diet: what the doctors say

Cancer and a plant based diet: what McDougall, Campbell, Ornish, Barnard and other doctors say and what their studies found, with sources.

Updated . For education only, not medical advice.

Our view

The doctors on this site start from the same observation: the common Western cancers of the breast, prostate and colon were far rarer in places such as rural Japan, rural China and Kenya, where people ate mostly starches and vegetables123. From that, McDougall, Campbell, Esselstyn and Rogers conclude that a rich diet of meat, dairy and fat drives these cancers, while Burkitt, the surgeon who mapped cancers in Africa, put the share of American cancers due to diet at perhaps a third24567.

Most of this rests on comparisons between countries, on laboratory rats and mice, and on single cases, which can point to causes but cannot prove what a diet does for one patient8910. The clearest human trial cited by these doctors is Dean Ornish’s: 93 men with early prostate cancer, all of whom had declined standard treatment, were split at random, and after one year the men who changed diet and lifestyle saw their PSA fall while the comparison group’s rose11. That trial measured a blood marker and the effect of the men’s blood on tumor cells in a dish, not survival12.

So we give most weight to what these doctors agree on and to their own cautions: a low-fat diet of whole plant foods is the best case they make for lowering risk, and none of them offers diet as a replacement for cancer care131415. When it comes to treating a cancer already there, even the strongest believers framed their view as opinion or as not yet proven, Campbell in 2023 and Pritikin in 19821610.

Where they agree

They agree that cancer rates move with diet: Esselstyn described Japanese families whose breast cancer rose to American levels after migrating, and Ornish made the same point about prostate cancer in Japan and the United States117. McDougall and Pritikin both pointed to populations living on rice, vegetables and little fat that rarely got breast, colon or prostate cancer218.

Animal protein and meat draw the most blame: Campbell calls casein, the main protein in cow’s milk, a strong promoter of tumors in his own reading of the evidence, and Rogers and Rip Esselstyn repeat that view192021. Barnard in 2025 and Novick in 2007 both tied red and processed meat to colorectal cancer, and Rip Esselstyn has warned about the compounds formed when meat is charred222324.

Fiber and the colon are another shared point: Burkitt held colon cancer to be almost wholly a matter of diet, and Rip Esselstyn in 2022 called fiber a strong defense against it2526. Novick and Rip Esselstyn both class alcohol as a known cause of cancer2728.

Where they differ

They part ways on what diet can do once a cancer is found, on fasting, on how much of cancer diet explains, and on which pills or foods help, and some views carry their dates7293031.

Diet after a diagnosis

McDougall, who says a journal accepted his study of diet for breast cancer in 1982, the first of its kind, said in 2011 that research shows a diet change helps people live longer after common cancers, without giving study sizes in that video3233. Campbell said in 2023 that, from early data, such a diet may hold a cancer steady, calling this his opinion and the choice a personal one16. Burkitt, in an interview posted in 2013, doubted that diet changes much once a tumor has formed and said he knew of no figures on it7. Ornish and Barnard both stressed that the prostate trial does not show standard treatment to be unneeded1514.

Fasting

Longo described mice that fasted before very high doses of chemotherapy surviving while fed mice died, and his 2015 paper found that repeated cycles of a fasting-like diet cut tumors in middle-aged mice349. Goldhamer, who runs a fasting center, cited that animal work in 2025 and said human studies had begun35. In 2026 he said every lymphoma his center had seen seemed to respond to fasting, pointing to published case reports and series, though he said a clinical trial was still lacking29.

How much of cancer diet explains

Campbell, judging from the gaps between countries, estimated in 2023 that eating whole plant foods might prevent 80 to 90% of cancers or more, calling it his view30. Burkitt estimated perhaps a third of American cancers come from diet7. Nelson in 2022 said a low-fat plant based diet lowers risk but offers no guarantee, and faulted Joel Fuhrman for calling common cancers completely avoidable1336.

Sugar and keto

McDougall in 2017 rejected the low-carb claim that sugar feeds cancer, noting that starch eaters such as the Seventh-day Adventists of Loma Linda show lower rates of breast, colon and prostate cancer3738. Rogers in 2026 described mice on keto whose original breast tumors grew more slowly but spread more often to the lungs, and judged keto for cancer unwise3940.

Pills and single foods

Barnard credited cruciferous vegetables with a specific anticancer action in 2024, through sulforaphane41. Novick was more doubtful of single items: in 2008 he found no evidence that chocolate prevents cancer and called the case for tea far from settled, and in 2011 he rated the evidence for vitamin D against cancer as weak424331. Nelson, speculating in 2022, suggested supplements and especially DHA as one possible factor, citing studies that tie DHA to higher cancer risk44.

Older views

In 1982 Pritikin leaned on the National Cancer Institute, which he said had singled out dietary fat as the chief cause of these cancers45. Esselstyn put Kenya’s lower breast cancer rate at 20 times in a 2009 talk and at 30 to 40 times in a lecture posted in 2014461.

What each expert says

John McDougall

McDougall blames the rich Western diet, heavy in fat, cholesterol and chemicals, for breast, prostate and colon cancer, and points to Asians living on rice and vegetables as the contrast2. In 2011 he said diet also matters after a diagnosis33. In 2017 he called the idea that sugar feeds cancer a low-carb notion that starch-eating populations contradict3738.

John on cancer: the full summary on John McDougall's page

Caldwell Esselstyn

Operating on breast cancer at the Cleveland Clinic, Esselstyn grew frustrated that each operation did nothing to protect the patient who came next, which turned him to nutrition46. He chose heart disease for his research because results come faster, hoping the same eating would also lower the common Western cancers47. His site’s FAQ, as we read it in 2026, credits plant based eating with a large drop in prostate cancer, and in a 2021 panel he cited Ornish’s finding that serum from plant based eaters slowed prostate cancer cells4849.

Caldwell on cancer: the full summary on Caldwell Esselstyn's page

T. Colin Campbell

Campbell’s rat studies on liver cancer found that a diet with 20% casein promoted tumors while 5% casein, or soy or wheat protein at the higher level, did not, work he described in a talk posted in 20185051. His China study, run with the Chinese government in the 1980s, surveyed 65 counties and 130 villages; it compared regions and had no treated and untreated groups3. In 2023 he said nutrition, more than chemicals, decides whether cancer develops4.

Colin on cancer: the full summary on T. Colin Campbell's page

Neal Barnard

Retelling Ornish’s trial in 2020, Barnard spoke of 84 men whose prostate cancer was progressing slowly: in the control group PSA climbed roughly 6%, while in the vegan group it went down, which he tied to lower IGF-152. He added that a diet change is no substitute for seeing a doctor14. In a cancer prevention talk posted in 2019, Barnard explained that the more fat a woman eats or carries, the more estrogen she makes, a hormone that can push breast cancer cells to grow53.

Neal on cancer: the full summary on Neal Barnard's page

Dean Ornish

With urologists Peter Carroll and William Fair, Ornish randomly assigned 93 men whose prostate cancer was confirmed by biopsy and who had opted against treatment; after a year, serum from the men who changed cut the growth of cultured tumor cells by 70%, compared with 9% for the untreated control men1112. His program’s 2012 video points out that far more men die with prostate cancer than because of it54. By 2019 he was citing trials where untreated men with early disease had survival close to that of men treated with surgery or radiation55.

Dean on cancer: the full summary on Dean Ornish's page

Alan Goldhamer

Goldhamer explains the fasting idea this way: normal cells adapt to low glucose and high ketones, while cancer cells do not and are left more exposed to treatment and the immune system56. Asked in 2026 about prostate cancer, he named diet, sleep, exercise and fasting as his first choices, citing Ornish’s research, and said he leaves medical management to the center’s physicians57.

Alan on cancer: the full summary on Alan Goldhamer's page

Peter Rogers

The first item on Rogers’ 2022 cancer prevention checklist was to eat no animal foods at all, dairy, fish and eggs included5. He links animal protein to methionine, which cancer cells need, and to the growth signals mTOR and IGF-15859.

Peter on cancer: the full summary on Peter Rogers's page

Jeff Novick

In 2007 Novick reported a large study in which the biggest eaters of red and processed meat had more colorectal and lung cancer23. The same year he wrote about the monks of Mount Athos, who ate mostly vegan, fasted often and worked daily, and whose prostate cancer rate was below one fourth of the global average60.

Jeff on cancer: the full summary on Jeff Novick's page

Jeff Nelson

In a 2022 video on several known vegans who got cancer, Nelson said eating low-fat and plant based, with a healthy lifestyle, lowers the odds but guarantees nothing13. He said nobody can know the causes in those cases and speculated about supplements, DHA in particular44.

Jeff on cancer: the full summary on Jeff Nelson's page

Rip Esselstyn

In a talk given around 2009, Rip Esselstyn blamed animal protein for promoting tumors and, during breast cancer awareness month, called eating plant based the cure the charity walks were looking for2161. In 2022 he tied slow movement of animal foods through the colon to colorectal cancer and named fiber as a defense26.

Rip on cancer: the full summary on Rip Esselstyn's page

Nathan Pritikin

In 1982 Pritikin told McDougall his diet could do people with cancer no harm and could perhaps help, but conceded that he had only isolated cases and no proof10. He described one woman with a stomach cancer given months to live who improved on his diet and stayed free of symptoms for the two years he followed her, though he allowed that spontaneous remission happens62.

Nathan on cancer: the full summary on Nathan Pritikin's page

Doug Lisle

Asked in 2024 by a viewer facing a poor prognosis after cancer treatment, Lisle said he would commit fully to healthy living rather than feel doomed63. He noted that a five-year survival figure of 11% still means 11 people out of 100 alive64.

Doug on cancer: the full summary on Doug Lisle's page

Denis Burkitt

Burkitt’s first research was the jaw tumor in Uganda that carries his name6. He argued that catching and treating a cancer early does nothing to make it less common, since only cutting its causes can do that65. He saw colon cancer as a disease of diet almost wholly, and tied breast cancer mostly to fat25.

Denis on cancer: the full summary on Denis Burkitt's page

Valter Longo

Longo’s explanation for his mouse results is that healthy cells protect themselves when food is short, while cancer cells cannot66. His 2014 study of 6,381 American adults tied a high protein intake between 50 and 65 to roughly a fourfold cancer death rate, a survey finding with no diet assigned67.

Valter on cancer: the full summary on Valter Longo's page

What we do in practice

We eat the low-fat, whole plant food diet these doctors describe for lowering risk, and none of them presents it as a substitute for cancer care131415. If you have cancer or are being checked for it, make every decision about treatment, fasting, supplements and medicines with your own doctor and oncologist, and never stop or replace a treatment on your own. This page is education, not medical advice.

Each small number links to its reference below: the video at the exact second, or the page where it was said.

References

  1. Esselstyn, "How to reverse heart disease", part 1, lecture for John McDougall (posted 2014) ↩1 ↩2 ↩3
  2. McDougall, "Dietary Treatment of Cancer", diet and cancer rates (2011) ↩1 ↩2 ↩3 ↩4
  3. Campbell, "CANCER: It's What's For Dinner" talk, the China study (posted 2018) ↩1 ↩2
  4. Campbell, "Use Your Diet to Prevent Diseases", Exam Room LIVE (2023) ↩1 ↩2
  5. Rogers, "Cancer prevention checklist, part 1", no animal foods (2022) ↩1 ↩2
  6. Denis Burkitt interviewed by John McDougall, Burkitt lymphoma (undated recording, posted 2013) ↩1 ↩2
  7. Denis Burkitt interviewed by John McDougall, diet and established cancer (undated recording, posted 2013) ↩1 ↩2 ↩3 ↩4
  8. Campbell, same talk, rats on 20% and 5% protein (posted 2018) ↩
  9. Brandhorst and others with Longo as senior author, a periodic diet that mimics fasting, Cell Metabolism (2015) ↩1 ↩2
  10. Pritikin interviewed by John McDougall, diet for people with cancer (1982 recording) ↩1 ↩2 ↩3
  11. Ornish on Good Morning America, prostate cancer study (posted 2011) ↩1 ↩2
  12. Ornish, same segment, tumor cells (posted 2011) ↩1 ↩2
  13. Nelson, "Too Many Vegans Getting Cancer" (2022) ↩1 ↩2 ↩3 ↩4
  14. Barnard, "Diet Myths 8 With Dr. Barnard", results of the prostate trial (2020) ↩1 ↩2 ↩3 ↩4
  15. Ornish, same segment, other treatments (posted 2011) ↩1 ↩2 ↩3
  16. Campbell, same 2023 Exam Room interview, existing cancer (2023) ↩1 ↩2
  17. Ornish, Charlie Rose interview, part 2, prostate cancer (posted 2011) ↩
  18. Pritikin interviewed by John McDougall, 25 low-fat populations (1982 recording) ↩
  19. Campbell, same 2023 Exam Room interview, casein (2023) ↩
  20. Rogers, same 2022 checklist, T. Colin Campbell (2022) ↩
  21. Rip Esselstyn, "Engine 2 Diet Will Save Your Life", talk, animal protein (posted 2018, given about 2009) ↩1 ↩2
  22. Barnard, "Live Longer with Diabetes, Heart Disease Eating This Diet", The Exam Room (2025) ↩
  23. Novick, "Red Meat and Colon Cancer, Again!" (blog, 2007; archived copy, 2007) ↩1 ↩2
  24. Rip Esselstyn, "Eat More to Weigh Less: Understanding Calorie Density", PLANTSTRONG live show, burned food (2022) ↩
  25. Denis Burkitt interviewed by John McDougall, colon and breast cancer (undated recording, posted 2013) ↩1 ↩2
  26. Rip Esselstyn, "Adding Fiber to Your Diet - Rip's Big Bowls!", PLANTSTRONG live show, colorectal cancer (2022) ↩1 ↩2
  27. Novick, forum reply "Breast Cancer & Alcohol" (2007; archived copy, 2007) ↩
  28. Rip Esselstyn, PLANTSTRONG site, "6 Reasons Why Alcohol Is Unhealthy" (book excerpt, 2017; on site 2023) ↩
  29. Goldhamer, "Fasting For Lymphoma, Is A Raw Vegan Diet Healthier, Omega 3 Testing & More", lymphoma (2026) ↩1 ↩2
  30. Campbell, same 2023 Exam Room interview, share of cancers (2023) ↩1 ↩2
  31. Novick, "Vitamin D, Calcium, Cancer & You!" (2011; archived copy, 2016) ↩1 ↩2
  32. McDougall, "Dietary Treatment of Cancer", his 1982 study (2011) ↩
  33. McDougall, same 2011 video, after diagnosis (2011) ↩1 ↩2
  34. Longo in the documentary Science of Fasting, the cancer mouse test (posted 2021) ↩
  35. Goldhamer, "Can Fasting Actually Save Your Life?" talk, chemotherapy in rats (2025) ↩
  36. Nelson, same 2022 video, the avoidability claim (2022) ↩
  37. McDougall, "Does Sugar Feed Cancer?" (2017) ↩1 ↩2
  38. McDougall, same 2017 talk, starch eaters and cancer (2017) ↩1 ↩2
  39. Rogers, "Keto diet increases risk of breast cancer metastases!" (2026) ↩
  40. Rogers, same 2026 video, his view (2026) ↩
  41. Barnard, "Five Foods To Eat For Weight Loss", Exam Room Podcast (2024) ↩
  42. Novick, forum reply on the book Foods That Fight Cancer, chocolate and cocoa (2008; archived copy, 2008) ↩
  43. Novick, same 2008 forum reply, tea (archived copy, 2008) ↩
  44. Nelson, same 2022 video, supplements (2022) ↩1 ↩2
  45. Pritikin interviewed by John McDougall, fat, oils and cancer (1982 recording) ↩
  46. Esselstyn, "Make Yourself Heart Attack Proof", talk, breast cancer (posted 2009) ↩1 ↩2
  47. Esselstyn, same part 1 lecture, why heart disease (posted 2014) ↩
  48. Esselstyn's site, FAQ, prostate cancer (page as read in 2026) ↩
  49. Esselstyn, "What Can We Do To Prevent Cancer?", panel with T. Colin Campbell, Baxter Montgomery and William Li (posted 2021) ↩
  50. Campbell, same talk, 5% protein and plant proteins (posted 2018) ↩
  51. Campbell, "T. Colin Campbell, PhD: Link Between Dairy Protein, Casein, & Cancer" (posted 2016) ↩
  52. Barnard, "Diet Myths 8 With Dr. Barnard", Ornish trial (2020) ↩
  53. Barnard, "Cancer Prevention Diet" talk, estrogen (posted 2019) ↩
  54. Ornish program video, "Slow, Stop, Reverse Cancer" (2012) ↩
  55. Ornish interviewed by John McDougall, webinar, prostate cancer trials (2019) ↩
  56. Goldhamer, same 2025 talk, normal and cancer cells (2025) ↩
  57. Goldhamer, same 2026 Q&A, prostate cancer (2026) ↩
  58. Rogers, same 2022 checklist, methionine (2022) ↩
  59. Rogers, same 2022 checklist, mTOR and IGF-1 (2022) ↩
  60. Novick, "Living Like A Monk: Reducing Cancer Risk (The Original Mediterranean Diet)" (2007; archived copy, 2026) ↩
  61. Rip Esselstyn, same talk, breast cancer month (posted 2018, given about 2009) ↩
  62. Pritikin interviewed by John McDougall, a case of stomach cancer (1982 recording) ↩
  63. Lisle with Chef AJ, Q&A on exercise, weight loss and hope with a cancer diagnosis (2024) ↩
  64. Lisle, same 2024 Q&A, survival figures (2024) ↩
  65. Denis Burkitt interviewed by John McDougall, prevention versus early diagnosis (undated recording, posted 2013) ↩
  66. Longo in the documentary Science of Fasting, cancer cells (posted 2021) ↩
  67. Levine, Suarez, Brandhorst and others with Longo as senior author, protein intake, IGF-1, cancer and mortality, Cell Metabolism (2014) ↩

Written in our own words from what each expert has said in public, for education only; it is not medical advice. How we make this site

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